Because of unhealthy habits, a particular human"s body is in perpetual unrest. With pathogens, microbes, and foreign agents everywhere, the responsibilities of many cells grow ever more arduous and perilous. Among those who have grown up in this turbulent setting, Sekkekkyuu AA2153 and Hakkekkyuu U-1196 endeavor to carry out their roles—even if it requires witnessing numerous fellow cells sacrifice themselves in service. Set against a backdrop far removed from its source material, Hataraku Saibou Black depicts the cells" battles to preserve bodily well‑being. Yet the human"s state keeps worsening, and whether these attempts yield tangible results hinges on the cells themselves. Their efforts echo through the bloodstream, highlighting cellular limits for the body.
