At Suimei High, the Sakura‑sou dorm is notorious for housing the school"s most infamous troublemakers. When the comparatively mild Sorata Kanda is assigned there, his first priority becomes breaking out of this chaotic refuge. While stuck for now, he must navigate life with his roommates—cheerful animator Misaki Kamiigusa, suave playboy author Jin Mitaka, and the withdrawn Ryuunosuke Akasaka. Amidst the oddities, Sorata often finds comfort in conversations with his sole "ordinary" companion, aspiring voice actress Nanami Aoyama.
The arrival of Mashiro Shiina, a new foreign exchange student, instantly captivates Sorata with her striking beauty. Beneath that ethereal façade lies an autistic savant whose artistic genius is world‑renowned, yet she struggles with everyday chores. When Sorata takes on the role of her caretaker, their bond deepens, and his original plan to flee fades into memory.
Each resident shines in a unique domain, leaving Sorata feeling bereft of any distinct talent. Surrounded by such brilliance, he resolves to match their gifts. Centered on the trials and triumphs of this vibrant ensemble, Sakura‑sou no Pet no Kanojo is a touching coming‑of‑age narrative about friendship, love, ambition, and heartbreak through the eyes of an ordinary boy amid extraordinary people.