As a child, Takashi Natsume considered his sight of youkai merely a curse. Now in high school, he has recovered from past pains and forged indestructible ties with both humans and spirits. His fresh alliances—especially the one with his guardian spirit Madara, dubbed "Nyanko-sensei"—often intertwine with the responsibility of restoring spirit names recorded in his late grandmother Reiko"s Book of Friends. Though extraordinary youkai approach him, Natsume realizes he still has much to grasp about the surrounding world and the mysteries of the unseen realms that shape their coexistence while he learns to balance compassion with weight of destiny.