U.S. Special Agent Leon S. Kennedy covertly enters a minor Eastern European nation to confirm reports that Bio‑Organic Weapons (B.O.W.s) are deployed in combat. Immediately after his incursion, the U.S. administration commands him to withdraw at once. Resolute in exposing reality, Leon disregards the directive and steps onto the front lines to halt the cycle of calamities wrought by B.O.W.s in earnest.
