Rebel group Reunion has reduced the city of Chernobog to ash and despair. That is merely the start of its revolt against nations that discriminate against those infected with the highly contagious and lethal disease Oripathy. Now the insurgents aim at Lungmen—a wealthy city notorious for its cruel treatment of patients. After seeing Reunion devastate her native land, Chief Ch'en of the Lungmen Guard Department"s Special Inspection Division leads his team to protect the city.
Meanwhile, Amiya, the Doctor, and the rest of the cutting‑edge pharmaceutical firm Rhodes Island continue to confront Reunion on all fronts. Yet they soon encounter a stalemate against a formidable foe: FrostNova, a Reunion commander whose chilling powers cause anyone unlucky enough to oppose her to gradually freeze to death in the icy wasteland beyond the ruined city.
