National University of Saitama, a forge of Japanese scientific talent. Two graduate students—Yukimura Shinya and Ayame Himuro—at one glorious moment realize that they are something more to each other than just friends and rivals in scientific activity, and confess their love. However, lacking any experience in personal relationships and being scientists to the bone, they immediately after their confession ask themselves: "Do we really love each other—and if so, is it possible to prove this by scientific method?" Thus begins the story of two inquisitive minds attempting to formulate an equation for true love between two specific people, who gradually become the talk of their colleagues and the entire laboratory.
